Event Title

Antibacterial Activity of Ethanol Extract from Salvia Officinalis (L.) Plant Growing Wild in Kosovo

Session

Medical, Chemical and Pharmaceutical Sciences

Description

In this study the antibacterial efficiency of ethanol extract from Salvia officinalis (L.) growing wild in Kosovo were examined. Ethanol extract was tested against two gram positive bacteria Staphylococus aureus (clinical isolate), Listeria monocytogenes (clinical isolate) and one gram negative bacteria Escherichia coli (clinical isolate). The antibacterial activity was determined by using agar disc diffusion method. The inhibition zone of extract was compared to that of penicillin G. The ethanol extract showed activity in all of the concentrations 1, 3 and 5 mg/mL towards E. coli, S. aureus and L. Monocytogenes. Ethanol extract of the plant with concentration 5 mg/mL showed a stronger antibacterial activity towards bacteria S. aureus with inhibition zone of 9 mm. The antibacterial activity of the S. officinalis (L.)was due to the presence of various secondary metabolites such as phenols and flavonoids. Hence, this plant can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals.

Keywords:

Salvia officinalis (L), antibacterial activity, agar disk diffusion method, ethanol extract

Session Chair

Arianit Jakupi

Session Co-Chair

Valon Ejupi

Proceedings Editor

Edmond Hajrizi

ISBN

978-9951-437-54-7

Location

Durres, Albania

Start Date

28-10-2017 9:00 AM

End Date

28-10-2017 10:30 AM

DOI

10.33107/ubt-ic.2017.295

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Oct 28th, 9:00 AM Oct 28th, 10:30 AM

Antibacterial Activity of Ethanol Extract from Salvia Officinalis (L.) Plant Growing Wild in Kosovo

Durres, Albania

In this study the antibacterial efficiency of ethanol extract from Salvia officinalis (L.) growing wild in Kosovo were examined. Ethanol extract was tested against two gram positive bacteria Staphylococus aureus (clinical isolate), Listeria monocytogenes (clinical isolate) and one gram negative bacteria Escherichia coli (clinical isolate). The antibacterial activity was determined by using agar disc diffusion method. The inhibition zone of extract was compared to that of penicillin G. The ethanol extract showed activity in all of the concentrations 1, 3 and 5 mg/mL towards E. coli, S. aureus and L. Monocytogenes. Ethanol extract of the plant with concentration 5 mg/mL showed a stronger antibacterial activity towards bacteria S. aureus with inhibition zone of 9 mm. The antibacterial activity of the S. officinalis (L.)was due to the presence of various secondary metabolites such as phenols and flavonoids. Hence, this plant can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals.