ESBL (Extended Spectrum Beta Lactamase) Infections - an Emerging Problem in Children
Session
Medical, Chemical and Pharmaceutical Sciences
Description
There is an emergence of infections with ESBL-producing micro-organisms recently. They remain poorly characterized in children. We sought to characterize children in a teaching hospital from whom an ESBL-producing organism had been isolated. We identified all children under sixteen years of age who had ESBL-producing organism isolated in the year 2016 in children admitted to pediatric hospital at University Hospital center “Mother Theresa”, Tirana. The referral source was contacted for further information where possible. Clinical details and treatment were analyzed to determine likelihood of infection or colonization. Fifteen children were identified, aged three months to nine years. Thirteen isolates were obtained from urine, one each from a wound swab and a cough swab. Three isolates were obtained from hospitalized children, but only one of these needed treatment. This child presented with lymphadenitis and continued to be pyrexial and irritable despite treatment with cephalosporin. Subsequently ESBL producing organism was isolated from the urine and she responded to appropriate antibiotic. Data was available for nine out of twelve patients originating from the community. Of these, four had repeat specimens which didn't grow ESBL-producer again. Three were treated and two remained asymptomatic and well. ESBL-producing organisms are increasingly isolated in children, but from our review appear frequently to be colonizers rather than pathogens. However, it is very important to be vigilant about the possibility of ESBL infection in children especially if they fail standard antibiotic therapy.
Keywords:
beta lactamase, wound
Session Chair
Besnik Elshani
Session Co-Chair
Petrit Biberaj
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-437-54-7
Location
Durres, Albania
Start Date
28-10-2017 2:00 PM
End Date
28-10-2017 3:30 PM
DOI
10.33107/ubt-ic.2017.301
Recommended Citation
Biberaj, Petrit, "ESBL (Extended Spectrum Beta Lactamase) Infections - an Emerging Problem in Children" (2017). UBT International Conference. 301.
https://knowledgecenter.ubt-uni.net/conference/2017/all-events/301
ESBL (Extended Spectrum Beta Lactamase) Infections - an Emerging Problem in Children
Durres, Albania
There is an emergence of infections with ESBL-producing micro-organisms recently. They remain poorly characterized in children. We sought to characterize children in a teaching hospital from whom an ESBL-producing organism had been isolated. We identified all children under sixteen years of age who had ESBL-producing organism isolated in the year 2016 in children admitted to pediatric hospital at University Hospital center “Mother Theresa”, Tirana. The referral source was contacted for further information where possible. Clinical details and treatment were analyzed to determine likelihood of infection or colonization. Fifteen children were identified, aged three months to nine years. Thirteen isolates were obtained from urine, one each from a wound swab and a cough swab. Three isolates were obtained from hospitalized children, but only one of these needed treatment. This child presented with lymphadenitis and continued to be pyrexial and irritable despite treatment with cephalosporin. Subsequently ESBL producing organism was isolated from the urine and she responded to appropriate antibiotic. Data was available for nine out of twelve patients originating from the community. Of these, four had repeat specimens which didn't grow ESBL-producer again. Three were treated and two remained asymptomatic and well. ESBL-producing organisms are increasingly isolated in children, but from our review appear frequently to be colonizers rather than pathogens. However, it is very important to be vigilant about the possibility of ESBL infection in children especially if they fail standard antibiotic therapy.