Event Title

Impact of Propofol on softening of the cough during arousal from anesthesia in children undergoing tonsillectomy

Session

Medicine and Nursing

Description

Interventions for surgical removal of tonsils in children are frequent, especially in school-age children. Since this intervention is done under general anesthesia, the most common event during anesthesia after tonsils removal is cough. In our research we have analyzed the effect of Propofol on reducing the frequency of cough presentation. Cough is a reflex response to the presence of foreign particles and injuries to the respiratory tract.Method: The study has prospective design, investigating the presence of an adverse anesthetic and post-surgical effect during arousal from anesthesia. The study included 240 children aged 3–15 years, operated by the tonsils, all rated ASA 1. Patients were divided into two equal groups, the experimental group and the control group. The experimental group was administered 0.5mg/kg Propofol and the control group 0.1mg/kg sodium chloride. The influence of age and duration of surgery on cough presentation was observed and recorded.The data processing was done with the In Stat 3 statistical package. From statistical parameters calculated the structure index, arithmetic mean, standard deviation, minimum and maximum values. Testing of qualitative data was done with X2 test and Fisher's exact test, and calculation of quantitative data that did not have normal distribution with Mann-Whitney test The correlation between the two phenomena was made with Spearman's correlation for nonparametric data. Test verification was done with 99.7% confidence level (P <0.01) and 95% confidence level (P <0.05). Results: Out of 120 patients in the study group of 10 or 8.3% presented cough, while from 120 patients of the control group are 23 or 19.2%. With the X2-test we obtained a distinction with the statistical signification of cough by groups presentation. Cough is more common in patients in the control group (X2-test = 5.1, P = 0.024, P <0.05). Conclusion: Administration of the sub-hypnotic dose of Propofol at the end of general anesthesia enables slow waking and few postanesthetic complications such as cough. The age and gender of the surgeons do not affect the incidence of cough presentation while the duration of the surgical intervention is a very important factor

Keywords:

Tonsillectomy, propofol, anaesthesia, cough

Session Chair

Syheda Latifi Hoxha

Session Co-Chair

Shqiptar Demaçi

Proceedings Editor

Edmond Hajrizi

ISBN

978-9951-550-19-2

Location

Pristina, Kosovo

Start Date

26-10-2019 1:30 PM

End Date

10-2019 3:00 PM

DOI

10.33107/ubt-ic.2019.317

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Oct 26th, 1:30 PM Oct 26th, 3:00 PM

Impact of Propofol on softening of the cough during arousal from anesthesia in children undergoing tonsillectomy

Pristina, Kosovo

Interventions for surgical removal of tonsils in children are frequent, especially in school-age children. Since this intervention is done under general anesthesia, the most common event during anesthesia after tonsils removal is cough. In our research we have analyzed the effect of Propofol on reducing the frequency of cough presentation. Cough is a reflex response to the presence of foreign particles and injuries to the respiratory tract.Method: The study has prospective design, investigating the presence of an adverse anesthetic and post-surgical effect during arousal from anesthesia. The study included 240 children aged 3–15 years, operated by the tonsils, all rated ASA 1. Patients were divided into two equal groups, the experimental group and the control group. The experimental group was administered 0.5mg/kg Propofol and the control group 0.1mg/kg sodium chloride. The influence of age and duration of surgery on cough presentation was observed and recorded.The data processing was done with the In Stat 3 statistical package. From statistical parameters calculated the structure index, arithmetic mean, standard deviation, minimum and maximum values. Testing of qualitative data was done with X2 test and Fisher's exact test, and calculation of quantitative data that did not have normal distribution with Mann-Whitney test The correlation between the two phenomena was made with Spearman's correlation for nonparametric data. Test verification was done with 99.7% confidence level (P <0.01) and 95% confidence level (P <0.05). Results: Out of 120 patients in the study group of 10 or 8.3% presented cough, while from 120 patients of the control group are 23 or 19.2%. With the X2-test we obtained a distinction with the statistical signification of cough by groups presentation. Cough is more common in patients in the control group (X2-test = 5.1, P = 0.024, P <0.05). Conclusion: Administration of the sub-hypnotic dose of Propofol at the end of general anesthesia enables slow waking and few postanesthetic complications such as cough. The age and gender of the surgeons do not affect the incidence of cough presentation while the duration of the surgical intervention is a very important factor