Testing the direct compaction properties of ground plant material to make a solid pharmaceutical form from mountain tea
Session
Pharmaceutical and Natural Sciences
Description
Sideritis scardica and Sideritis raeseri (mountain tea) are widely utilized in Mediterranean traditional medicine in the form of either a decoction or infusion. The aim of this study is preparation of a solid pharmaceutical form from mountain tea. Testing the direct compaction properties of aerial part plant material (homogenized samples from flower, leaf and stem) the direct compaction properties of ground plant material above ground tea using a roller compactor, without the addition of solvents and other excipients as a binder, showed very weak compaction properties, and it was impossible to obtain good quality of ribbon and granules, primarily due to the uneven size of the crushed mass and hence the problematic flow. This is due to the specific morphological structure and the presence of a large number of mechanical fibers in the form of trichomes in mountain tea.
Keywords:
mountain tea, compaction, rroller compactor, trichomes.
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-550-47-5
First Page
1
Start Date
30-10-2021 12:00 AM
End Date
30-10-2021 12:00 AM
DOI
10.33107/ubt-ic.2021.78
Recommended Citation
Qazimi, Bujar; Dodov, Marija Glavas; Stefkov, Gjoshe; Ejupi, Valon; Dragusha, Shpend; Alidema, Fitim; Karapandzova, Marija; Karanfilova, Ivana Cvetkovikj; and Kulevanova, Svetlana, "Testing the direct compaction properties of ground plant material to make a solid pharmaceutical form from mountain tea" (2021). UBT International Conference. 145.
https://knowledgecenter.ubt-uni.net/conference/2021UBTIC/all-events/145
Testing the direct compaction properties of ground plant material to make a solid pharmaceutical form from mountain tea
Sideritis scardica and Sideritis raeseri (mountain tea) are widely utilized in Mediterranean traditional medicine in the form of either a decoction or infusion. The aim of this study is preparation of a solid pharmaceutical form from mountain tea. Testing the direct compaction properties of aerial part plant material (homogenized samples from flower, leaf and stem) the direct compaction properties of ground plant material above ground tea using a roller compactor, without the addition of solvents and other excipients as a binder, showed very weak compaction properties, and it was impossible to obtain good quality of ribbon and granules, primarily due to the uneven size of the crushed mass and hence the problematic flow. This is due to the specific morphological structure and the presence of a large number of mechanical fibers in the form of trichomes in mountain tea.