Interactions between drugs in patients with chronic polytherapy

Session

Pharmaceutical and Natural Sciences

Description

Studies carried out in different countries have shown an increase in the occurrence of drug interactions, especially in elderly patients. Physiological changes, alterations in homeostatic regulation and diseases modify pharmacokinetics and drug response in older patients. This presentation gives a reflection on polytherapy and interactions between drugs based on scientific literature. Main objective of topics focuses on analysis and evaluation of interactions between drugs in patients with chronic polytherapy and how much attention is paid by healthcare professionals, especially by doctors and pharmacists. Based on this statistical analysis, the results showed that there was a considerable number of interactions between drugs, so in 100 analysed patients were reported 24 major interactions, 292 moderate, 54 minor, and in 9 patients there was no interactions between drugs that they use. Major interactions are highly clinically significant, those combination of drugs should be avoided and repleaced with other drug.

Keywords:

Polytherapy, drug interactions, major, moderate, minor

Proceedings Editor

Edmond Hajrizi

ISBN

978-9951-550-47-5

First Page

1

Location

UBT Kampus, Lipjan

Start Date

30-10-2021 12:00 AM

End Date

30-10-2021 12:00 AM

DOI

10.33107/ubt-ic.2021.86

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Oct 30th, 12:00 AM Oct 30th, 12:00 AM

Interactions between drugs in patients with chronic polytherapy

UBT Kampus, Lipjan

Studies carried out in different countries have shown an increase in the occurrence of drug interactions, especially in elderly patients. Physiological changes, alterations in homeostatic regulation and diseases modify pharmacokinetics and drug response in older patients. This presentation gives a reflection on polytherapy and interactions between drugs based on scientific literature. Main objective of topics focuses on analysis and evaluation of interactions between drugs in patients with chronic polytherapy and how much attention is paid by healthcare professionals, especially by doctors and pharmacists. Based on this statistical analysis, the results showed that there was a considerable number of interactions between drugs, so in 100 analysed patients were reported 24 major interactions, 292 moderate, 54 minor, and in 9 patients there was no interactions between drugs that they use. Major interactions are highly clinically significant, those combination of drugs should be avoided and repleaced with other drug.