An update of reported potential side effects for selected drugs based on WHO pharmacovigilance database
Session
Pharmaceutical and Natural Sciences
Description
Adverse reactions of drugs can decrease compliance and delay recovery. Therefore, it is crucial to consider potential side effects when choosing particular drugs.
Analyzing the World Health Organization (WHO) pharmacovigilance database (Vigibase®), we collected Adverse Drug Reactions (ADRs) of selected drugs reported for decades.
Common side effects of omeprazole are renal and urinary disorders (18%), gastrointestinal disorders (15%), nervous system disorders (7%), cardiac disorders (2%). For ranitidine, neoplasms benign, malignant and unspecified (73%), followed by skin and subcutaneous tissue disorders (4%), vascular disorders (1%) were among reported ADRs. Ramipril caused respiratory system and breast disorders (15%), nervous system disorders (10%), cardiac disorders (10%). Atenolol mostly is associated with cardiac disorders (13%) and psychiatric disorders (6%). Paracetamol side effects counts gastrointestinal disorders (10%) hepatobiliary disorders (5%), immune system disorders (2%). Nimesulide usage may cause blood and lymphatic system disorders (2%), cardiac disorders (2%), ear and labyrinth disorders (1%). For ketoprofene, potential side effects are skin and subcutaneous tissue disorders (31%), nervous system disorders (5%), eye disorders (4%).
Even though there is no perfect drug that works quickly and completely free of adverse reaction, aim is to choose safer drugs, better tolerated, and associated with lower rate of noncompliance.
Keywords:
Pharmacovigilance, drugs, adverse reaction, recovery.
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-550-50-5
Start Date
29-10-2022 12:00 AM
End Date
30-9-2022 12:00 AM
DOI
10.33107/ubt-ic.2022.104
Recommended Citation
Ejupi, Valon; Qazimi, Bujar; Jakupi, Arianit; and Dragusha, Shpend, "An update of reported potential side effects for selected drugs based on WHO pharmacovigilance database" (2022). UBT International Conference. 104.
https://knowledgecenter.ubt-uni.net/conference/2022/all-events/104
An update of reported potential side effects for selected drugs based on WHO pharmacovigilance database
Adverse reactions of drugs can decrease compliance and delay recovery. Therefore, it is crucial to consider potential side effects when choosing particular drugs.
Analyzing the World Health Organization (WHO) pharmacovigilance database (Vigibase®), we collected Adverse Drug Reactions (ADRs) of selected drugs reported for decades.
Common side effects of omeprazole are renal and urinary disorders (18%), gastrointestinal disorders (15%), nervous system disorders (7%), cardiac disorders (2%). For ranitidine, neoplasms benign, malignant and unspecified (73%), followed by skin and subcutaneous tissue disorders (4%), vascular disorders (1%) were among reported ADRs. Ramipril caused respiratory system and breast disorders (15%), nervous system disorders (10%), cardiac disorders (10%). Atenolol mostly is associated with cardiac disorders (13%) and psychiatric disorders (6%). Paracetamol side effects counts gastrointestinal disorders (10%) hepatobiliary disorders (5%), immune system disorders (2%). Nimesulide usage may cause blood and lymphatic system disorders (2%), cardiac disorders (2%), ear and labyrinth disorders (1%). For ketoprofene, potential side effects are skin and subcutaneous tissue disorders (31%), nervous system disorders (5%), eye disorders (4%).
Even though there is no perfect drug that works quickly and completely free of adverse reaction, aim is to choose safer drugs, better tolerated, and associated with lower rate of noncompliance.