Hemogram parameters related to glucose and HbA1c values, in patients with type II diabetes. Effect of blood volume in EDTA tube on HbA1c result

Session

Medicine and Nursing

Description

ntroduction: Diabetes mellitus is a chronic metabolic disorder that causes hyperglycemia and various life-threatening health problems. Hematological parameters play an important role in the progression and pathogenesis of diabetes. Purpose: The purpose of this research is to determine possible changes in hemogram parameters in patients with type 2 diabetes. Materials and methods: To determine the possible relationship between hemogram parameters and the disease of diabetes 2, the patients were divided into two groups; with HbA1c up to 7.8% and with HbA1c values>7.8%. To determine the concentrations of HbA1c and glucose, blood was collected in 2 mL tubes containing K3-EDTA from 95 patients, in the Medical Laborato- ry,,Biolab Zafi,,-F in Peja and the Polyclinic Laboratory,,,Biolab -Zafi,, in the clinic from 01.02.2024 to 15.07.2024. Results: Mean and standard deviation of monocyte count, basophil count, monocyte %, basophil %, RBC count, hematocrit, MCV, MCH, RDW-SD, MPV, PDW, PLC-R and platelets showed a significant difference between patients with type 2 diabetes divided according to HbA1c values. The Pearson correlation coefficient showed that the total number of Leukocytes, the number of neutrophils, the number of monocytes, the number of basophils, RDW-CV, PDW, MPV, PLC-R and platelets were statistical- ly positively related to the concentration of glucose while the number of Erythrocytes, Hgb, hematocrit, MCV, , and RDW-SD were statistically negatively associated with glucose concentration in patients with type 2 diabetes. Conclusion: Based on the results of our study, it can be concluded that patients with type 2 diabetes may have abnormalities in various hematological parameters. It is recommended to regularly test hematological parameters for early diagnosis and appro- priate management of diabetes-related complications.

Keywords:

Type 2 diabetes, hemogram parameters, glucose, HbA1c.

Proceedings Editor

Edmond Hajrizi

ISBN

978-9951-982-15-3

Location

UBT Kampus, Lipjan

Start Date

25-10-2024 9:00 AM

End Date

27-10-2024 6:00 PM

DOI

10.33107/ubt-ic.2024.381

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Oct 25th, 9:00 AM Oct 27th, 6:00 PM

Hemogram parameters related to glucose and HbA1c values, in patients with type II diabetes. Effect of blood volume in EDTA tube on HbA1c result

UBT Kampus, Lipjan

ntroduction: Diabetes mellitus is a chronic metabolic disorder that causes hyperglycemia and various life-threatening health problems. Hematological parameters play an important role in the progression and pathogenesis of diabetes. Purpose: The purpose of this research is to determine possible changes in hemogram parameters in patients with type 2 diabetes. Materials and methods: To determine the possible relationship between hemogram parameters and the disease of diabetes 2, the patients were divided into two groups; with HbA1c up to 7.8% and with HbA1c values>7.8%. To determine the concentrations of HbA1c and glucose, blood was collected in 2 mL tubes containing K3-EDTA from 95 patients, in the Medical Laborato- ry,,Biolab Zafi,,-F in Peja and the Polyclinic Laboratory,,,Biolab -Zafi,, in the clinic from 01.02.2024 to 15.07.2024. Results: Mean and standard deviation of monocyte count, basophil count, monocyte %, basophil %, RBC count, hematocrit, MCV, MCH, RDW-SD, MPV, PDW, PLC-R and platelets showed a significant difference between patients with type 2 diabetes divided according to HbA1c values. The Pearson correlation coefficient showed that the total number of Leukocytes, the number of neutrophils, the number of monocytes, the number of basophils, RDW-CV, PDW, MPV, PLC-R and platelets were statistical- ly positively related to the concentration of glucose while the number of Erythrocytes, Hgb, hematocrit, MCV, , and RDW-SD were statistically negatively associated with glucose concentration in patients with type 2 diabetes. Conclusion: Based on the results of our study, it can be concluded that patients with type 2 diabetes may have abnormalities in various hematological parameters. It is recommended to regularly test hematological parameters for early diagnosis and appro- priate management of diabetes-related complications.