EVALUATION OF VITAMIN D STATUS IN SEASONAL SERUM SAMPLES
Session
Medicine and Nursing
Description
Introduction: Today, the measurement of vitamin D is usually performed for the diagnosis of osteoporosis and the establishment of an appropriate concentration that would effectively prevent the occurrence of other human diseases. The purpose of this study was to determine if the season, namely the time of the year in which the sample is taken for analysis, can affect the concentration of total vitamin D in the population of the Dugagjin Plain in the Republic of Kosovo. Material and Method: In two laboratories; The "Biolab-Zafi-F" Medical Laboratory in the city of Peja and the "Biolab-Zafi" Pol- yclinic laboratory in Klina have conducted a retrospective study to determine the values of total vitamin D (25-hydroxyvitamin D) in serum analyzed in patients with without hospitalization aged >58 years in the time period from 01.01.2022 to 31.08.2024. Vitamin D concentration assays were performed with the cobas e 411 analyzer, a fully automated analyzer using an Electro- ChemiLuminescence (ECL) technology. Results: The number of serum samples that we had determined vitamin D for the mentioned period was 863 outpatients, men and women. Vitamin D concentration was consistently lower in serum samples during winter than during the other three seasons dur- ing a calendar year. Multivariate analysis showed that the concentration of total vitamin D was independent of the gender and the season of blood analysis, but not of the age of the patients. Conclusion: According to the results, the season of blood sampling for vitamin D determination should be considered as an im- portant preanalytical factor in the estimation of vitamin D concentration. The amount of vitamin D synthesized during the sum- mer season should be sufficient for maintain the concentration > 45 -55 nmol/L during the rest of the year.
Keywords:
vitamin D, preanalytical variability, season
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-982-15-3
Location
UBT Kampus, Lipjan
Start Date
25-10-2024 9:00 AM
End Date
27-10-2024 6:00 PM
DOI
10.33107/ubt-ic.2024.382
Recommended Citation
Gashi, Zafer; Elezaj, Shkelzen; Gashi, Fatjona; Lahu, Fisnik; Elezaj, Gentian; Elezaj, Liridon; and Gashi, Fitim, "EVALUATION OF VITAMIN D STATUS IN SEASONAL SERUM SAMPLES" (2024). UBT International Conference. 37.
https://knowledgecenter.ubt-uni.net/conference/2024UBTIC/MN/37
EVALUATION OF VITAMIN D STATUS IN SEASONAL SERUM SAMPLES
UBT Kampus, Lipjan
Introduction: Today, the measurement of vitamin D is usually performed for the diagnosis of osteoporosis and the establishment of an appropriate concentration that would effectively prevent the occurrence of other human diseases. The purpose of this study was to determine if the season, namely the time of the year in which the sample is taken for analysis, can affect the concentration of total vitamin D in the population of the Dugagjin Plain in the Republic of Kosovo. Material and Method: In two laboratories; The "Biolab-Zafi-F" Medical Laboratory in the city of Peja and the "Biolab-Zafi" Pol- yclinic laboratory in Klina have conducted a retrospective study to determine the values of total vitamin D (25-hydroxyvitamin D) in serum analyzed in patients with without hospitalization aged >58 years in the time period from 01.01.2022 to 31.08.2024. Vitamin D concentration assays were performed with the cobas e 411 analyzer, a fully automated analyzer using an Electro- ChemiLuminescence (ECL) technology. Results: The number of serum samples that we had determined vitamin D for the mentioned period was 863 outpatients, men and women. Vitamin D concentration was consistently lower in serum samples during winter than during the other three seasons dur- ing a calendar year. Multivariate analysis showed that the concentration of total vitamin D was independent of the gender and the season of blood analysis, but not of the age of the patients. Conclusion: According to the results, the season of blood sampling for vitamin D determination should be considered as an im- portant preanalytical factor in the estimation of vitamin D concentration. The amount of vitamin D synthesized during the sum- mer season should be sufficient for maintain the concentration > 45 -55 nmol/L during the rest of the year.