Gastroesophageal Reflux associated with Lercanidipine
Session
Medicine and Nursing
Description
Although calcium channel antagonists target cardiac and vascular smooth muscle, their impact extends to other types of smooth muscles as well. In the gastrointestinal tract, blocking calcium influx can reduce gastric motility and lower esophage- al sphincter pressure, potentially affecting digestive processes.Lercanidipine is a medication that has only recently become avail- able in the Kosovar market. To our knowledge, there have been no reported cases of gastroesophageal reflux as a side effect of this drug. Over the past four years, our clinic has observed 34 patients who developed symptoms of gastroesophageal reflux after beginning calcium antagonist therapy for hypertension. Among these 34 patients, 8 were taking lercanidipine, while the remain- ing patients were on amlodipine, verapamil, and diltiazem. In conclusion, the use of calcium channel antagonists is not recom- mended In patients with hiatal hernia and hypertension because they can either cause or worsen reflux.
Keywords:
gastroesophageal reflux disease, lercanidipine.
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-982-15-3
Location
UBT Kampus, Lipjan
Start Date
25-10-2024 9:00 AM
End Date
27-10-2024 6:00 PM
DOI
10.33107/ubt-ic.2024.352
Recommended Citation
Telaku, Mimoza and Telaku, Skender, "Gastroesophageal Reflux associated with Lercanidipine" (2024). UBT International Conference. 7.
https://knowledgecenter.ubt-uni.net/conference/2024UBTIC/MN/7
Gastroesophageal Reflux associated with Lercanidipine
UBT Kampus, Lipjan
Although calcium channel antagonists target cardiac and vascular smooth muscle, their impact extends to other types of smooth muscles as well. In the gastrointestinal tract, blocking calcium influx can reduce gastric motility and lower esophage- al sphincter pressure, potentially affecting digestive processes.Lercanidipine is a medication that has only recently become avail- able in the Kosovar market. To our knowledge, there have been no reported cases of gastroesophageal reflux as a side effect of this drug. Over the past four years, our clinic has observed 34 patients who developed symptoms of gastroesophageal reflux after beginning calcium antagonist therapy for hypertension. Among these 34 patients, 8 were taking lercanidipine, while the remain- ing patients were on amlodipine, verapamil, and diltiazem. In conclusion, the use of calcium channel antagonists is not recom- mended In patients with hiatal hernia and hypertension because they can either cause or worsen reflux.