Causes of Endodontic Treatment Failure

Presenter Information

Hajrie Dauti

Session

Dental Science

Description

Endodontic treatment is considered a highly predictable procedure for preserving teeth affected by pulpal and periapical diseases. Nevertheless, treatment failure remains a clinical challenge, often leading to persistent symptoms or tooth loss. Identifying the underlying causes is crucial to improving prognosis.This review is based on an analysis of current literature from PubMed, Scopus, and Google Scholar (2010–2024), focusing on clinical trials, systematic reviews, and case reports addressing causes of endodontic treatment failure.The main factors associated with failure include inadequate cleaning and disinfection of root canals, complex canal morphology, incomplete instrumentation, and insufficient obturation. Other contributing elements are coronal leakage, vertical root fractures, persistent bacterial infections (notably Enterococcus faecalis), and misdiagnosis. Studies report failure rates ranging from 10–20% depending on technique and follow-up period.A comprehensive understanding of the biological, anatomical, and technical causes of endodontic failure is essential for prevention. The adoption of modern instrumentation systems, improved irrigation protocols, use of bioceramic sealers, and proper coronal restoration significantly enhance the long-term success of endodontic therapy.

Keywords:

Endodontics, treatment failure, root canal therapy, obturation, coronal restoration

Proceedings Editor

Edmond Hajrizi

ISBN

978-9951-982-41-2

Location

UBT Lipjan, Kosovo

Start Date

25-10-2025 9:00 AM

End Date

26-10-2025 6:00 PM

DOI

10.33107/ubt-ic.2025.120

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Oct 25th, 9:00 AM Oct 26th, 6:00 PM

Causes of Endodontic Treatment Failure

UBT Lipjan, Kosovo

Endodontic treatment is considered a highly predictable procedure for preserving teeth affected by pulpal and periapical diseases. Nevertheless, treatment failure remains a clinical challenge, often leading to persistent symptoms or tooth loss. Identifying the underlying causes is crucial to improving prognosis.This review is based on an analysis of current literature from PubMed, Scopus, and Google Scholar (2010–2024), focusing on clinical trials, systematic reviews, and case reports addressing causes of endodontic treatment failure.The main factors associated with failure include inadequate cleaning and disinfection of root canals, complex canal morphology, incomplete instrumentation, and insufficient obturation. Other contributing elements are coronal leakage, vertical root fractures, persistent bacterial infections (notably Enterococcus faecalis), and misdiagnosis. Studies report failure rates ranging from 10–20% depending on technique and follow-up period.A comprehensive understanding of the biological, anatomical, and technical causes of endodontic failure is essential for prevention. The adoption of modern instrumentation systems, improved irrigation protocols, use of bioceramic sealers, and proper coronal restoration significantly enhance the long-term success of endodontic therapy.