A New Electrochemical Sensor for determination of Vitamin B6

Session

Pharmaceutical and Natural Sciences

Description

A new electrochemical sensor for determination of Vitamin B6 was designed using carbon paste electrodes modified with several metallophthalocyanines such as FePc, NiPc, CoPc, and CuPc. The modification of the electrode with iron phtalocyanine showed the highest electrocatalytic activity towards Vitamin B6 determination. Cyclic voltammetry was employed to investigate the electrochemical behavior of the analyte, while differential pulse voltammetry was used for sensitive quantitative experiments with all optimized experimental parameters. Vitamin B6 exhibited a clear oxidation peak at around +1.0 V vs. Ag/AgCl using BrittonRobinson buffer solution. The sensor showed a linear concentration range of 5–100 mM with a detection limit of 2.82 mM and demonstrated reliable repeatability and reproducibility. This method offers a cost-effective, and robust tool for vitamin B6 analysis in various samples including pharmaceuticals.

Keywords:

Pyridoxine, Cyclic Voltammetry, Carbon Paste Electrode, Metallophthalocyanine, Electrochemical sensor

Proceedings Editor

Edmond Hajrizi

ISBN

978-9951-982-41-2

Location

UBT Lipjan, Kosovo

Start Date

25-10-2025 9:00 AM

End Date

26-10-2025 6:00 PM

DOI

10.33107/ubt-ic.2025.348

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Oct 25th, 9:00 AM Oct 26th, 6:00 PM

A New Electrochemical Sensor for determination of Vitamin B6

UBT Lipjan, Kosovo

A new electrochemical sensor for determination of Vitamin B6 was designed using carbon paste electrodes modified with several metallophthalocyanines such as FePc, NiPc, CoPc, and CuPc. The modification of the electrode with iron phtalocyanine showed the highest electrocatalytic activity towards Vitamin B6 determination. Cyclic voltammetry was employed to investigate the electrochemical behavior of the analyte, while differential pulse voltammetry was used for sensitive quantitative experiments with all optimized experimental parameters. Vitamin B6 exhibited a clear oxidation peak at around +1.0 V vs. Ag/AgCl using BrittonRobinson buffer solution. The sensor showed a linear concentration range of 5–100 mM with a detection limit of 2.82 mM and demonstrated reliable repeatability and reproducibility. This method offers a cost-effective, and robust tool for vitamin B6 analysis in various samples including pharmaceuticals.