ADDRESSING OXIDATIVE STRESS USING NANOTECHNOLOGY: PROMISES AND CHALLANGES
Session
Pharmaceutical and Natural Sciences
Description
An imbalance between the formation of reactive oxygen species (ROS) and the reaction of antioxidant proteins is referred to as oxidative stress. Numerous pathogenic illnesses, including persistent infections, inflammatory disorders, cardiovascular diseases, neurological diseases, and cancer, are thought to be triggered by reactive oxygen (ROS), reactive nitrogen (RNS), and reactive sulphur (RSS) species. Despite significant effort over the past few decades to translate antioxidant therapy into clinical practice, the majority of clinical trials utilizing general antioxidant therapy have failed, most likely as a result of a lack of understanding of the redox signaling pathways in health and disease. The effective use of nanocomplex systems as nano-antioxidants using nanotechnology has emerged as a potential path. The intersection of nanotechnologies with molecular biology can function to improve human health by improving the cross-link of oxidative stress and inflammation. However, understanding how to manipulate the substance to determine its function in the body and how the body will respond to this substance is necessary for the transition from laboratory investigations to clinical translation. Therefore, nanotechnology provides an efficient route to address oxidative stress-related diseases by providing tailored antioxidant administration, mitochondria protection, ROS scavenging, and improved diagnostics.
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-550-95-6
Location
UBT Lipjan, Kosovo
Start Date
28-10-2023 8:00 AM
End Date
29-10-2023 6:00 PM
DOI
10.33107/ubt-ic.2023.118
Recommended Citation
Saha, Sarmistha, "ADDRESSING OXIDATIVE STRESS USING NANOTECHNOLOGY: PROMISES AND CHALLANGES" (2023). UBT International Conference. 13.
https://knowledgecenter.ubt-uni.net/conference/IC/PNS/13
ADDRESSING OXIDATIVE STRESS USING NANOTECHNOLOGY: PROMISES AND CHALLANGES
UBT Lipjan, Kosovo
An imbalance between the formation of reactive oxygen species (ROS) and the reaction of antioxidant proteins is referred to as oxidative stress. Numerous pathogenic illnesses, including persistent infections, inflammatory disorders, cardiovascular diseases, neurological diseases, and cancer, are thought to be triggered by reactive oxygen (ROS), reactive nitrogen (RNS), and reactive sulphur (RSS) species. Despite significant effort over the past few decades to translate antioxidant therapy into clinical practice, the majority of clinical trials utilizing general antioxidant therapy have failed, most likely as a result of a lack of understanding of the redox signaling pathways in health and disease. The effective use of nanocomplex systems as nano-antioxidants using nanotechnology has emerged as a potential path. The intersection of nanotechnologies with molecular biology can function to improve human health by improving the cross-link of oxidative stress and inflammation. However, understanding how to manipulate the substance to determine its function in the body and how the body will respond to this substance is necessary for the transition from laboratory investigations to clinical translation. Therefore, nanotechnology provides an efficient route to address oxidative stress-related diseases by providing tailored antioxidant administration, mitochondria protection, ROS scavenging, and improved diagnostics.