THE CHROMIUM AND VANADIUM IMPACT ON LIPID METABOLISM IN WORKERS EXPOSED TO CFA
Session
Pharmaceutical and Natural Sciences
Description
Chromium (Cr) and vanadium (V) are elements that in trace amounts have impact in carbohydrate and lipid metabolism, but at high concentrations can be toxic, depending on the form. Data from previous studies prove the effect of Cr and V concentrations on lipid metabolism, especially in workers exposed to coal fly ash (CFA).
Selected metals (Cr, V) were measured in the samples of blood and serum from workers located in Thermal Power Plants in Kosovo and have been analyzed with the reference values. Using a biochemical analyzer Synchron CX7 (Beckman Coulter) have been analyzed the lipid profile. The blood and serum Cr and V was measured by inductively coupled plasma mass spectrometry.
The association between carbohydrate and lipid metabolism biomarkers (glucose, cholesterol, and triglycerides) and co-exposure to coal fly ash was analyzed. The workers who are part of the Thermal Power Plants had significantly higher blood Cr and V levels (p < 0.0001) and significantly lower serum Cr and V levels (p < 0.0001) than the control group. Statistically significant (p < 0.0001) correlations between high blood Cr levels and low glucose/blood Cr ratios as well as between high serum Cr levels and low glucose/serum Cr ratios was established. The analyzed group have high blood V levels significantly correlated with low triglycerides/blood V and cholesterol/blood V ratios (p < 0.0001), while high serum V levels correlated with low cholesterol/serum V ratios (p = 0.005). Based on results, the glucose/Cr, triglycerides/V and cholesterol/V ratios should be considered when evaluating carbohydrate and lipid metabolism disorders in occupationally-exposed workers.
Keywords:
chromium; vanadium; lipid metabolism; correlation
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-550-95-6
Location
UBT Lipjan, Kosovo
Start Date
28-10-2023 8:00 AM
End Date
29-10-2023 6:00 PM
DOI
10.33107/ubt-ic.2023.111
Recommended Citation
Bajraktari, Demush and Zeneli, Lulzim, "THE CHROMIUM AND VANADIUM IMPACT ON LIPID METABOLISM IN WORKERS EXPOSED TO CFA" (2023). UBT International Conference. 5.
https://knowledgecenter.ubt-uni.net/conference/IC/PNS/5
THE CHROMIUM AND VANADIUM IMPACT ON LIPID METABOLISM IN WORKERS EXPOSED TO CFA
UBT Lipjan, Kosovo
Chromium (Cr) and vanadium (V) are elements that in trace amounts have impact in carbohydrate and lipid metabolism, but at high concentrations can be toxic, depending on the form. Data from previous studies prove the effect of Cr and V concentrations on lipid metabolism, especially in workers exposed to coal fly ash (CFA).
Selected metals (Cr, V) were measured in the samples of blood and serum from workers located in Thermal Power Plants in Kosovo and have been analyzed with the reference values. Using a biochemical analyzer Synchron CX7 (Beckman Coulter) have been analyzed the lipid profile. The blood and serum Cr and V was measured by inductively coupled plasma mass spectrometry.
The association between carbohydrate and lipid metabolism biomarkers (glucose, cholesterol, and triglycerides) and co-exposure to coal fly ash was analyzed. The workers who are part of the Thermal Power Plants had significantly higher blood Cr and V levels (p < 0.0001) and significantly lower serum Cr and V levels (p < 0.0001) than the control group. Statistically significant (p < 0.0001) correlations between high blood Cr levels and low glucose/blood Cr ratios as well as between high serum Cr levels and low glucose/serum Cr ratios was established. The analyzed group have high blood V levels significantly correlated with low triglycerides/blood V and cholesterol/blood V ratios (p < 0.0001), while high serum V levels correlated with low cholesterol/serum V ratios (p = 0.005). Based on results, the glucose/Cr, triglycerides/V and cholesterol/V ratios should be considered when evaluating carbohydrate and lipid metabolism disorders in occupationally-exposed workers.