Intra-Alveolar Application of Clindamycin- Impact in reducing the incidence of Complications following Surgical Removal of Mandibular Third Molar

Session

Medical, Chemical and Pharmaceutical Sciences

Description

The most commonly performed surgical procedures in oral surgery are extractions of third mandibular teeth. Complications following the extraction of third mandibular teeth which may occur are pain, alveolar osteitis, and edema. The purpose of this study was to determinate if the effectiveness of intra-alveolar application of Clindamycin could reduce the incidence of pain, alveolar osteitis and edema after the extraction of third mandibular tooth in nonsmoker patients. Patients who qualified for the prospective, randomized, placebo-controlled trial were nonsmokers. In a group of 30 patients, mandibular third molars in both sides were extracted on the same day. In total 60 third mandibular molars were extracted. The left side was a study group in which we applied the Clindamycin intra alveolary, and the right side was a control group. Tooth extraction was performed under local anesthesia. At 1, 2, and 5 days after surgery, postextraction evaluation was recorded by the same examiner.The results demonstrate an effectiveness of intra-alveolar application of Clindamycin in reducing the incidence of pain (with Clindamycin M 45.7 vs. without Clindamycin 18.7) but not in reducing alveolar osteitis and edema.

Keywords:

pain, alveolar osteitis, edema, nonsmokers, Clindamycin

Session Chair

Burim Kiseri

Session Co-Chair

Vjosa Hamiti Krasniqi

Proceedings Editor

Edmond Hajrizi

ISBN

978-9951-437-54-7

Location

Durres, Albania

Start Date

28-10-2017 4:00 PM

End Date

28-10-2017 5:30 PM

DOI

10.33107/ubt-ic.2017.304

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Oct 28th, 4:00 PM Oct 28th, 5:30 PM

Intra-Alveolar Application of Clindamycin- Impact in reducing the incidence of Complications following Surgical Removal of Mandibular Third Molar

Durres, Albania

The most commonly performed surgical procedures in oral surgery are extractions of third mandibular teeth. Complications following the extraction of third mandibular teeth which may occur are pain, alveolar osteitis, and edema. The purpose of this study was to determinate if the effectiveness of intra-alveolar application of Clindamycin could reduce the incidence of pain, alveolar osteitis and edema after the extraction of third mandibular tooth in nonsmoker patients. Patients who qualified for the prospective, randomized, placebo-controlled trial were nonsmokers. In a group of 30 patients, mandibular third molars in both sides were extracted on the same day. In total 60 third mandibular molars were extracted. The left side was a study group in which we applied the Clindamycin intra alveolary, and the right side was a control group. Tooth extraction was performed under local anesthesia. At 1, 2, and 5 days after surgery, postextraction evaluation was recorded by the same examiner.The results demonstrate an effectiveness of intra-alveolar application of Clindamycin in reducing the incidence of pain (with Clindamycin M 45.7 vs. without Clindamycin 18.7) but not in reducing alveolar osteitis and edema.