The evolution of the approach towards the antibiotic prophylaxis of infective endocarditis before invasive dental procedures
Session
Dental Science
Description
Background
Infective endocarditis is a rare disease with a high morbidity and mortality. For more than 50 years antibiotic prophylaxis before dental invasive procedures has been the primary focus for preventing infective endocarditis and has remained the standard of care for patients with the disease in most parts of the world.
Objectives
This paper aims to describe the evolution of the approach towards the antibiotic prophylaxis of infective endocarditis before invasive dental procedures. Reviewing and comparing different guidelines and studies performed before and after the implementation of these guidelines, we attempt to give an historic and also up-to-date panorama of the strategies used to prevent infective endocarditis. We also aim to provide sound arguments to simplify decision-making for the dental community when dealing with susceptible patients.
Methods
Electronic searches were conducted across databases such as Pubmed Central, Cochrane Register of Controlled Trials, Centre for reviews, Science Directand PubMed using keywords such as antibiotic prophylaxis, infective endocarditis. Additional reports were identified from the reference lists of retrieved reports and from review articles of the same subject. After screening of the titles and available full text articles were retrieved. Finally titles of interest for the review were found and they have been included in the review.
Conclusions
Considering the difficulty of the treatment of IE, in the course of the years a significant emphasis has been put on using antibiotic prophylaxis on susceptible patients empirically in order to prevent it. Several guidelines and protocols were designed in order to help clinicians in the decision-making process of administering antibiotics prior to dental procedures. Anyway, the guidelines regarding IE have evolved and nowadays, they all point toward a general trend against empiric use of antibiotic prophylaxis for infective endocarditis. Considering the effects of cummulative bacteremia, the emphasis nowadays is on the maintenance of an optimal oral hygiene and the absence of gingival disease as the best strategy to prevent infective endocarditis in susceptible patients
Keywords:
antibiotic prophylaxis, bacterial endocarditis
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-550-19-2
Location
Pristina, Kosovo
Start Date
27-10-2019 11:30 AM
End Date
27-10-2019 11:45 AM
DOI
10.33107/ubt-ic.2019.175
Recommended Citation
Shkreta, Mirsad and Dollaku, Blerta, "The evolution of the approach towards the antibiotic prophylaxis of infective endocarditis before invasive dental procedures" (2019). UBT International Conference. 175.
https://knowledgecenter.ubt-uni.net/conference/2019/events/175
The evolution of the approach towards the antibiotic prophylaxis of infective endocarditis before invasive dental procedures
Pristina, Kosovo
Background
Infective endocarditis is a rare disease with a high morbidity and mortality. For more than 50 years antibiotic prophylaxis before dental invasive procedures has been the primary focus for preventing infective endocarditis and has remained the standard of care for patients with the disease in most parts of the world.
Objectives
This paper aims to describe the evolution of the approach towards the antibiotic prophylaxis of infective endocarditis before invasive dental procedures. Reviewing and comparing different guidelines and studies performed before and after the implementation of these guidelines, we attempt to give an historic and also up-to-date panorama of the strategies used to prevent infective endocarditis. We also aim to provide sound arguments to simplify decision-making for the dental community when dealing with susceptible patients.
Methods
Electronic searches were conducted across databases such as Pubmed Central, Cochrane Register of Controlled Trials, Centre for reviews, Science Directand PubMed using keywords such as antibiotic prophylaxis, infective endocarditis. Additional reports were identified from the reference lists of retrieved reports and from review articles of the same subject. After screening of the titles and available full text articles were retrieved. Finally titles of interest for the review were found and they have been included in the review.
Conclusions
Considering the difficulty of the treatment of IE, in the course of the years a significant emphasis has been put on using antibiotic prophylaxis on susceptible patients empirically in order to prevent it. Several guidelines and protocols were designed in order to help clinicians in the decision-making process of administering antibiotics prior to dental procedures. Anyway, the guidelines regarding IE have evolved and nowadays, they all point toward a general trend against empiric use of antibiotic prophylaxis for infective endocarditis. Considering the effects of cummulative bacteremia, the emphasis nowadays is on the maintenance of an optimal oral hygiene and the absence of gingival disease as the best strategy to prevent infective endocarditis in susceptible patients