INCIDENCE OF POSTSTREPTOCOCCAL ACUTE GLOMERULONEPHRITIS AND LABORATORY AND CLINICAL SIGNS IN PATIENTS WITH THIS DISEASE AT THE NEPHROLOGY UNITE IN PEDIATRIC CLINIC – PERIOD JANUARY – DECEMBER 2018
Session
Medicine and Nursing
Description
The aim of the study was to evaluate the incidence and prevalence of GNAPS at our patients with kidney disease, than to evaluate the causes of it, and to monitor clinical signs and laboratory data. Our attention is on finding the causes and conditions that can contribute on occurrence of the disease. We have described the most important clinical signs and laboratory results, in order to draw the conclusions for prevention of the disease and to impact on minimizing the consequences of the disease .
Our patients, 37 of them, have been the children hospitalized in Pediatric clinic of Prishtina – Nephrology ward. The group age of the patient was from 28 days to 18 years during the perid January 2018 – December 2018.
According to the history data, laboratory tests and other additional examination, statistical processing we have achieve these results: Within total number of children with Acute poststreptococcocal glomerulonephritis 67.5% were male and 32.4 % were female which mean 2:1 respectively. The vulnerable age is between 6 to 15 years with 75.6 %. Less vulnerable age is from 15 to 18 years with 8.1 %. The children from the villages are most affected by the disease with 62.1 % while the children from cities with 37.8 % . Regarding the social status of the patient we have found from our study that Acute poststreptococcocal glomerulonephritis is the disease of the families with low incomes. From our study 45.9 % of the patients are with low economic status 18.9 % with middle economic status and 8.1 with high economic status. From the etiological aspects we have concluded that most of the infections are caused by St. beta hemoliticum but the high percentage of Acute poststreptococcocal glomerulonephritis 24.3 % is caused by piodermic infections. Regarding the importance for the clinical signs different authors have made a different separations. We have given the importance to these signs: oliguria, edema and hypertension . With oliguria were 78.3 % , with edema 72.9 % and 40.5 % with hypertension. We have to emphasize that most of the patients were presented with two clinical signs like oliguria and edema and sometimes combined with hypertension . Only a small number of patients were presented with one sign.
According to the laboratory tests 97.2 % of the patients have had microscopic hematuria and 89.1 % proteinuria.
Regarding the hematologic tests we have found 43.2 % of patients with high sedimentation rates from 20 to 40. In many cases (81 %) there has been a decrease of the number of RBC that according to some authors is of dilutional character. Number of leukocites is increased as well (67.5 %).
Biochemical tests like urea and creatinine are within normal ranges. Sometimes they are slightly increased.
Serological tests of Acute poststreptococcocal glomerulonephritis are more significant, 70 % of patients were found with increased level of Antistrptolizin test O.
Most often complications of our patients were Acute Renal Insufficiency and Chronic Renal Insufficiency with equal percentage 6.1 %.
Patients were treated with antibiotics, antihypertensive drugs and very rare with imunossupresant.
Occurrence of the disease is often in winter, late autumn and early spring
Keywords:
Glolerulonephritis, childs, clinical signs, oedema.
Session Chair
Haki Jashari
Session Co-Chair
Eglantina Kraja Bardhi
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-550-19-2
Location
Pristina, Kosovo
Start Date
26-10-2019 3:30 PM
End Date
26-10-2019 5:00 PM
DOI
10.33107/ubt-ic.2019.319
Recommended Citation
Gashi, Nijazi, "INCIDENCE OF POSTSTREPTOCOCCAL ACUTE GLOMERULONEPHRITIS AND LABORATORY AND CLINICAL SIGNS IN PATIENTS WITH THIS DISEASE AT THE NEPHROLOGY UNITE IN PEDIATRIC CLINIC – PERIOD JANUARY – DECEMBER 2018" (2019). UBT International Conference. 319.
https://knowledgecenter.ubt-uni.net/conference/2019/events/319
INCIDENCE OF POSTSTREPTOCOCCAL ACUTE GLOMERULONEPHRITIS AND LABORATORY AND CLINICAL SIGNS IN PATIENTS WITH THIS DISEASE AT THE NEPHROLOGY UNITE IN PEDIATRIC CLINIC – PERIOD JANUARY – DECEMBER 2018
Pristina, Kosovo
The aim of the study was to evaluate the incidence and prevalence of GNAPS at our patients with kidney disease, than to evaluate the causes of it, and to monitor clinical signs and laboratory data. Our attention is on finding the causes and conditions that can contribute on occurrence of the disease. We have described the most important clinical signs and laboratory results, in order to draw the conclusions for prevention of the disease and to impact on minimizing the consequences of the disease .
Our patients, 37 of them, have been the children hospitalized in Pediatric clinic of Prishtina – Nephrology ward. The group age of the patient was from 28 days to 18 years during the perid January 2018 – December 2018.
According to the history data, laboratory tests and other additional examination, statistical processing we have achieve these results: Within total number of children with Acute poststreptococcocal glomerulonephritis 67.5% were male and 32.4 % were female which mean 2:1 respectively. The vulnerable age is between 6 to 15 years with 75.6 %. Less vulnerable age is from 15 to 18 years with 8.1 %. The children from the villages are most affected by the disease with 62.1 % while the children from cities with 37.8 % . Regarding the social status of the patient we have found from our study that Acute poststreptococcocal glomerulonephritis is the disease of the families with low incomes. From our study 45.9 % of the patients are with low economic status 18.9 % with middle economic status and 8.1 with high economic status. From the etiological aspects we have concluded that most of the infections are caused by St. beta hemoliticum but the high percentage of Acute poststreptococcocal glomerulonephritis 24.3 % is caused by piodermic infections. Regarding the importance for the clinical signs different authors have made a different separations. We have given the importance to these signs: oliguria, edema and hypertension . With oliguria were 78.3 % , with edema 72.9 % and 40.5 % with hypertension. We have to emphasize that most of the patients were presented with two clinical signs like oliguria and edema and sometimes combined with hypertension . Only a small number of patients were presented with one sign.
According to the laboratory tests 97.2 % of the patients have had microscopic hematuria and 89.1 % proteinuria.
Regarding the hematologic tests we have found 43.2 % of patients with high sedimentation rates from 20 to 40. In many cases (81 %) there has been a decrease of the number of RBC that according to some authors is of dilutional character. Number of leukocites is increased as well (67.5 %).
Biochemical tests like urea and creatinine are within normal ranges. Sometimes they are slightly increased.
Serological tests of Acute poststreptococcocal glomerulonephritis are more significant, 70 % of patients were found with increased level of Antistrptolizin test O.
Most often complications of our patients were Acute Renal Insufficiency and Chronic Renal Insufficiency with equal percentage 6.1 %.
Patients were treated with antibiotics, antihypertensive drugs and very rare with imunossupresant.
Occurrence of the disease is often in winter, late autumn and early spring