Creutzfeldt-Jakob disease - Case report
Session
Medicine and Nursing
Description
Jakob-Creutzfeldt disease is a degenerative disorder that causes dementia and eventually death. It is usually diagnosed in the advanced stages because it gives a variety of atypical symptoms until the final stages. This case presentation aims to reflect the case of a woman with pronounced cognitive and psychiatric symptoms and her diagnostic journey until shortly before her death.
Case report: The 63-year-old patient had gradually started with subtle psychic changes, in the form of paranoid ideas, anxiety, a state of generally depressed mood, and changes in personality. Gradually the changes became more pronounced and in the last two weeks before hospitalization, she changed completely, slowing down and manifesting a state of psychomotor disturbance with visual hallucinations. After wandering through several clinics of the UCCK, she is hospitalized at the Neurological Department, where a lumbar puncture, MRI of the brain, and EEG are performed. The final diagnosis was made after the arrival of the results, i.e. imaging changes in the nucleus lentiform, nucleus caudatus, and bilateral corona radiata; specific sharp triphasic waves in the EEG and finally the identification of the 14-3-3 protein in the cerebrospinal fluid.
Conclusion: CJDdisease is rare, but it should be considered in the differential diagnosis as we often have patients with progressive cognitive and psychic changes, along with symptoms such as myoclonus and visual hallucinations.
Keywords:
Creutzfeldt-Jakob disease, cognitive decline, psychic changes, neurodegenerative disorder.
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-550-50-5
Location
UBT Kampus, Lipjan
Start Date
29-10-2022 12:00 AM
End Date
30-10-2022 12:00 AM
DOI
10.33107/ubt-ic.2022.186
Recommended Citation
Alidema, Arieta Hasani and Pushka, Melihate, "Creutzfeldt-Jakob disease - Case report" (2022). UBT International Conference. 188.
https://knowledgecenter.ubt-uni.net/conference/2022/all-events/188
Creutzfeldt-Jakob disease - Case report
UBT Kampus, Lipjan
Jakob-Creutzfeldt disease is a degenerative disorder that causes dementia and eventually death. It is usually diagnosed in the advanced stages because it gives a variety of atypical symptoms until the final stages. This case presentation aims to reflect the case of a woman with pronounced cognitive and psychiatric symptoms and her diagnostic journey until shortly before her death.
Case report: The 63-year-old patient had gradually started with subtle psychic changes, in the form of paranoid ideas, anxiety, a state of generally depressed mood, and changes in personality. Gradually the changes became more pronounced and in the last two weeks before hospitalization, she changed completely, slowing down and manifesting a state of psychomotor disturbance with visual hallucinations. After wandering through several clinics of the UCCK, she is hospitalized at the Neurological Department, where a lumbar puncture, MRI of the brain, and EEG are performed. The final diagnosis was made after the arrival of the results, i.e. imaging changes in the nucleus lentiform, nucleus caudatus, and bilateral corona radiata; specific sharp triphasic waves in the EEG and finally the identification of the 14-3-3 protein in the cerebrospinal fluid.
Conclusion: CJDdisease is rare, but it should be considered in the differential diagnosis as we often have patients with progressive cognitive and psychic changes, along with symptoms such as myoclonus and visual hallucinations.