ANTIBIOTIC PROPHYLAXIS OF INFECTIONS IN MAXILLOFACIAL REGION

Presenter Information

Sinan Rusinovci

Session

Dental Sciences

Description

The vast majority of dental abscesses respond to antibiotic treatment, however, in some patients surgical management of the infection may be indicated.

The aims was to investigate the role and efficacy of antibiotics prophylaxis for the prevention of surgical site infections after periapical surgical approaches caused after failed endodontic treatments. 102 patients were incorporated in the study and additionally 50 patients were included into the study as healthy controls with no concomitant abscesses. The samples were collected from abscess and from healthy side of gingiva of the same patient with abscess and also the samples are taken from the healthy controls from different site of oral cavity.

102 pus samples from patients with dental abscesses were examined for bacterial growth and samples from healthy gingiva of healthy individuals were swabbed for comparison of bacterial etiology. In total 254 swab samples were collected and sent for bacterial inoculation.

Isolated pathogenic bacterial were compared and bacteria identified using MALDI-TOF.

Bacterial strains were identified in 92 out of 102 patients with dental abscesses.

We isolated 16 different bacterial species from 102 patients with dentoalveolar abscesses.

In 40 (39.2%) out of the 102 samples only aerobic flora was present, in 16 (15.7%) out of 102 only strictly anaerobic flora, and in 46 (45.1%) out of 102 abscesses mixed aerobic anaerobic flora was isolated. In 61 (50.0%) out of 102 cases same microorganism was identified from healthy side of oral cavity and from the sample of abscesses. In 13 samples of the patients only polymicrobial infections could be evaluated, thus this samples were categorized as the same infection agents as identified from healthy swabs.

Isolated oral microorganisms in our study did not vary with significance compared to healthy oral microbiota, thus commensal microbiota were the main cause of dental abscesses. Cultivating and culture testing take time providing results in few days, what is usually too late, and modern methods of microbial identification are expensive. Most of oral microbiota is uncultivable therefore modern methods of identification are necessary, especially at polymicrobial infections.

The use of antibiotics for the management of dentoalveolar infections should be considered only in the presence of an increased risk of a systemic involvement or to prevent metastatic infections.

Keywords:

Dentoalveolar abscesses, Oral microbiota, Maxillofacial surgery, MALDI-ToF/Tof -MS, Bacterial identifiation

Proceedings Editor

Edmond Hajrizi

ISBN

978-9951-550-50-5

Location

UBT Kampus, Lipjan

Start Date

29-10-2022 12:00 AM

End Date

30-10-2022 12:00 AM

DOI

10.33107/ubt-ic.2022.220

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Oct 29th, 12:00 AM Oct 30th, 12:00 AM

ANTIBIOTIC PROPHYLAXIS OF INFECTIONS IN MAXILLOFACIAL REGION

UBT Kampus, Lipjan

The vast majority of dental abscesses respond to antibiotic treatment, however, in some patients surgical management of the infection may be indicated.

The aims was to investigate the role and efficacy of antibiotics prophylaxis for the prevention of surgical site infections after periapical surgical approaches caused after failed endodontic treatments. 102 patients were incorporated in the study and additionally 50 patients were included into the study as healthy controls with no concomitant abscesses. The samples were collected from abscess and from healthy side of gingiva of the same patient with abscess and also the samples are taken from the healthy controls from different site of oral cavity.

102 pus samples from patients with dental abscesses were examined for bacterial growth and samples from healthy gingiva of healthy individuals were swabbed for comparison of bacterial etiology. In total 254 swab samples were collected and sent for bacterial inoculation.

Isolated pathogenic bacterial were compared and bacteria identified using MALDI-TOF.

Bacterial strains were identified in 92 out of 102 patients with dental abscesses.

We isolated 16 different bacterial species from 102 patients with dentoalveolar abscesses.

In 40 (39.2%) out of the 102 samples only aerobic flora was present, in 16 (15.7%) out of 102 only strictly anaerobic flora, and in 46 (45.1%) out of 102 abscesses mixed aerobic anaerobic flora was isolated. In 61 (50.0%) out of 102 cases same microorganism was identified from healthy side of oral cavity and from the sample of abscesses. In 13 samples of the patients only polymicrobial infections could be evaluated, thus this samples were categorized as the same infection agents as identified from healthy swabs.

Isolated oral microorganisms in our study did not vary with significance compared to healthy oral microbiota, thus commensal microbiota were the main cause of dental abscesses. Cultivating and culture testing take time providing results in few days, what is usually too late, and modern methods of microbial identification are expensive. Most of oral microbiota is uncultivable therefore modern methods of identification are necessary, especially at polymicrobial infections.

The use of antibiotics for the management of dentoalveolar infections should be considered only in the presence of an increased risk of a systemic involvement or to prevent metastatic infections.