Addressing Interplay of Oxidative Stress & Inflammation using Nanotechnology
Session
Pharmaceutical and Natural Sciences
Description
An imbalance between the formation of reactive oxygen species (ROS) and the reaction of antioxidant proteins is referred to as oxidative stress. On the other hand, inflammation influences various pathological consequences such as cancer, Alzheimer’s disease, atherosclerosis, and many others. Inflammation and metabolism are intricately intertwined, considering numerous metabolic and cardiovascular disorders exhibit chronic low-grade inflammation. Despite significant effort over the past few decades to translate antioxidant therapy into clinical practice, the majority of clinical trials utilizing general antioxidant therapy have failed, most likely as a result of a lack of understanding of the redox signaling pathways in health and disease. The effective use of nanocomplex systems as nano-antioxidants using nanotechnology has emerged as a potential path. The intersection of nanotechnologies with molecular biology can function to improve human health by improving the cross-link of oxidative stress and inflammation. However, understanding how to manipulate the substance to determine its function in the body and how the body will respond to this substance is necessary for the transition from laboratory investigations to clinical translation. Therefore, nanotechnology provides an efficient route to address oxidative stress-related diseases by providing tailored antioxidant administration, mitochondria protection, ROS scavenging, and improved diagnostics.
Keywords:
Oxidativ stress, Inflamations, Nanotechnology, Therapy
Proceedings Editor
Edmond Hajrizi
ISBN
978-9951-982-15-3
Location
UBT Kampus, Lipjan
Start Date
25-10-2024 9:00 AM
End Date
27-10-2024 6:00 PM
DOI
10.33107/ubt-ic.2024.165
Recommended Citation
Saha, Sarmishta, "Addressing Interplay of Oxidative Stress & Inflammation using Nanotechnology" (2024). UBT International Conference. 10.
https://knowledgecenter.ubt-uni.net/conference/2024UBTIC/PNS/10
Addressing Interplay of Oxidative Stress & Inflammation using Nanotechnology
UBT Kampus, Lipjan
An imbalance between the formation of reactive oxygen species (ROS) and the reaction of antioxidant proteins is referred to as oxidative stress. On the other hand, inflammation influences various pathological consequences such as cancer, Alzheimer’s disease, atherosclerosis, and many others. Inflammation and metabolism are intricately intertwined, considering numerous metabolic and cardiovascular disorders exhibit chronic low-grade inflammation. Despite significant effort over the past few decades to translate antioxidant therapy into clinical practice, the majority of clinical trials utilizing general antioxidant therapy have failed, most likely as a result of a lack of understanding of the redox signaling pathways in health and disease. The effective use of nanocomplex systems as nano-antioxidants using nanotechnology has emerged as a potential path. The intersection of nanotechnologies with molecular biology can function to improve human health by improving the cross-link of oxidative stress and inflammation. However, understanding how to manipulate the substance to determine its function in the body and how the body will respond to this substance is necessary for the transition from laboratory investigations to clinical translation. Therefore, nanotechnology provides an efficient route to address oxidative stress-related diseases by providing tailored antioxidant administration, mitochondria protection, ROS scavenging, and improved diagnostics.